Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 5, Issue 23, Pages 3745-3757Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b711244k
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To address the specific challenges of cancer therapy and diagnosis, a number of approaches have been advocated for the development of tumor-targeting antitumor drugs/prodrugs and non-invasive tumor molecular imaging probes. These intelligent drugs and probes are constructed from multi-functional molecular systems. This review focuses on the molecular design of drugs and imaging probes that target tumor-specific microenvironments such as angiogenesis and hypoxia.
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