Journal
JOURNAL OF BIOMECHANICS
Volume 40, Issue 11, Pages 2559-2563Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2006.11.007
Keywords
stress; strain; stiffness; cerebral artery; hypertension; biomechanics
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Funding
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL064372, R01HL080415] Funding Source: NIH RePORTER
- NHLBI NIH HHS [HL-80415, HL-64372] Funding Source: Medline
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Vascular cells are very responsive to even subtle changes in their local mechanical environment, thus there is a pressing need to quantify normal states of stress and strain as well as any perturbations from these normal states. Toward this end, we must quantify constitutive behaviors for both normal and adapted (maladapted) arteries. In this note, we report the first quantification of changes in the biaxial mechanical behavior of the passive basilar artery due to hypertension. (C) 2006 Elsevier Ltd. All rights reserved.
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