Journal
JOURNAL OF PROTEOME RESEARCH
Volume 6, Issue 7, Pages 2565-2575Publisher
AMER CHEMICAL SOC
DOI: 10.1021/pr070012k
Keywords
EAE; multiple sclerosis; iTRAQ; mass spectrometry; spinal cord
Categories
Funding
- NINDS NIH HHS [P30 NS046593, R01 NS046363, NS046363, NS046593, P30 NS046593-04, R01 NS046363-04, F31 NS054336] Funding Source: Medline
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P30NS046593, F31NS054336, R01NS046363] Funding Source: NIH RePORTER
Ask authors/readers for more resources
The present study used isobaric tags for relative and absolute quantitation (iTRAQ) to identify novel targets in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. The expression of 41 proteins was significantly altered in the inflamed spinal cord. Twenty of these are implicated in EAE for the first time and many have previously been shown to play a role in antigen processing, inflammation, neuroprotection, or neurodegeneration.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
