4.3 Article

Stero- and regioselective thiolysis of 1,2-epoxides in water

Journal

SYNTHETIC COMMUNICATIONS
Volume 37, Issue 18, Pages 3239-3244

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910701548100

Keywords

epoxides; beta-hydroxy sulfides; thiols; thiolysis; water

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A simple, efficient, stereoselective, and highly regioselective procedure for the synthesis of beta-hydroxy sulfides by thiolysis of various 1,2-epoxides in water as a solvent, using no catalyst and under very mild conditions, is described.

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