4.3 Article

L-proline-catalyzed asymmetric direct aldol reaction of heteroaromatic aldehydes and acetone: Improvement of catalytic efficiency in ionic liquid bmim [BF4]

Journal

SYNTHETIC COMMUNICATIONS
Volume 37, Issue 22-24, Pages 4301-4307

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910701575574

Keywords

asymmetric aldol; enantiomeric excess; heteroaromatic aldehlydes; beta-hydroxy carbonyl compounds; ionic liquid; L-proline

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L-proline in bmim [BF4] ionic liquid has been successfully used as an efficient and reusable catalyst for the direct asymmetric aldol reaction of acetone with different heteroaromatic aldehydes to afford higher selectivity of the aldol products with good enantioselectivity.

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