Journal
JOURNAL OF BIOMECHANICS
Volume 40, Issue 9, Pages 1887-1902Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.jbiomech.2006.09.003
Keywords
abdominal aortic aneurysm; AAA biomechanics; AAA rupture; aortic wall stress; intraluminal thrombus; aortic wall strength; aneurysm wall weakening
Categories
Funding
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL060670, R01HL079313] Funding Source: NIH RePORTER
- NHLBI NIH HHS [R01 HL060670-02, R01 HL060670-08, R01 HL079313, R01 HL060670-07, R01 HL060670-06, R01 HL079313-01A1, R01 HL060670-03, R01 HL079313-03, R01 HL060670-05A1, R01 HL060670-04, R01-HL-060670, R01 HL079313-02, R01 HL060670, R01-HL-079313, R01 HL060670-01A2, R01 HL079313-04] Funding Source: Medline
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Abdominal aortic aneurysm (AAA) is a condition whereby the terminal aorta permanently dilates to dangerous proportions, risking rupture. The biornechanics of AAA has been studied with great interest since aneurysm rupture is a mechanical failure of the degenerated aortic wall and is a significant cause of death in developed countries. In this review article, the importance of considering the biomechanics of AAA is discussed, and then the history and the state-of-the-art of this field is reviewed-including investigations into the biomechanical behavior of AAA tissues, modeling AAA wall stress and factors which influence it, and the potential clinical utility of these estimates in predicting AAA rupture. (C) 2006 Elsevier Ltd. All rights reserved.
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