Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Volume 25, Issue 4, Pages 667-680Publisher
WILEY
DOI: 10.1002/jmri.20866
Keywords
nanotechnology; contrast agents; imaging; drug therapy; atherosclerosis
Funding
- NATIONAL CANCER INSTITUTE [U54CA119342] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL042950, R01HL059865] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB001704] Funding Source: NIH RePORTER
- OFFICE OF THE DIRECTOR, NCI [N01CO007121] Funding Source: NIH RePORTER
- NCI NIH HHS [U54-CA-119342, N01-CO-07121] Funding Source: Medline
- NHLBI NIH HHS [HL-073646, HL-42950, HL-59865] Funding Source: Medline
- NIBIB NIH HHS [EB-01704] Funding Source: Medline
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Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site-targeted treatment with nanoparticle delivery systems.
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