Journal
NATURE PROTOCOLS
Volume 2, Issue 7, Pages 1675-1684Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nprot.2007.206
Keywords
-
Categories
Funding
- NCRR NIH HHS [5M01RR 00827-29] Funding Source: Medline
- NINDS NIH HHS [NS-45563] Funding Source: Medline
- NATIONAL CENTER FOR RESEARCH RESOURCES [M01RR000827] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [T35NS045563] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Measuring changes in the characteristics of corticospinal output has become a critical part of assessing the impact of motor experience on cortical organization in both the intact and injured human brain. In this protocol we describe a method for systematically assessing training-induced changes in corticospinal output that integrates volumetric anatomical MRI with transcranial magnetic stimulation (TMS). A TMS coil is sited to a target grid superimposed onto a 3D MRI of cortex using a stereotaxic neuronavigation system. Subjects are then required to exercise the first dorsal interosseus (FDI) muscle on two different tasks for a total of 30 min. The protocol allows for reliably and repeatedly detecting changes in corticospinal output to FDI muscle in response to brief periods of motor training.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available