cTrans: Generating polypeptide databases from cDNA sequences

cTrans is a comprehensive utility used to generate polypeptide databases from cDNA sequences. Received: July 13, 2006 The goal is achieved through integrating four main functions, including retrieving sequences of Revised: September 20, 2006 species of interest from the downloaded packages from dbEST of GenBank, format conversion, Accepted: October 8, 2006 checking and deleting vector and adaptor contamination, and translating the cDNA sequences in all six frames and selecting specific translations for database construction in a user-defined length threshold. In addition, this utility is also applicable to cDNA sequences produced by users themselves.