4.7 Article

Addressing a vascular endothelium array with blood components using underlying microfluidic channels

Journal

LAB ON A CHIP
Volume 7, Issue 10, Pages 1256-1259

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b712619k

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Funding

  1. NIBIB NIH HHS [EB 000482-01] Funding Source: Medline
  2. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB000482] Funding Source: NIH RePORTER

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Here, we show that an array of endothelial cells, addressable by an underlying microfluidic network of channels containing red blood cells, can be employed as an in vitro model of in vivo circulation to monitor cellular communication between different cell types in the drug discovery process.

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