4.1 Article Proceedings Paper

Toward a catalytic site in DNA: Polyaza crown ether as non-nucleosidic building blocks in DNA conjugates

Journal

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volume 26, Issue 10-12, Pages 1419-1422

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/15257770701539260

Keywords

polyaza crown ether; catalysis; DNA-conjugates

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A number of functionalized polyaza crown ether building blocks have been incorporated into DNA-conjugates as catalytic Cu2+ binding sites. The effect of the DNA-conjugate catalyst. on the stereochemical outcome of a Cu2+-catalyzed Diels-Alder reaction will be presented.

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