Journal
GENOME BIOLOGY
Volume 8, Issue 5, Pages -Publisher
BIOMED CENTRAL LTD
DOI: 10.1186/gb-2007-8-5-r81
Keywords
high-density tiling microarray; high-density oligonucleotide microarray; microarray data analysis
Funding
- NCRR NIH HHS [1 S10 RR19895-01, S10 RR019895] Funding Source: Medline
- NHGRI NIH HHS [1U01HG003156-01, U01 HG003156] Funding Source: Medline
- NIDDK NIH HHS [P30 DK072442, 5P30DK072442-02] Funding Source: Medline
- NLM NIH HHS [T15 LM07056, T15 LM007056] Funding Source: Medline
- NATIONAL CENTER FOR RESEARCH RESOURCES [S10RR019895] Funding Source: NIH RePORTER
- NATIONAL HUMAN GENOME RESEARCH INSTITUTE [U01HG003156] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [P30DK072442] Funding Source: NIH RePORTER
- NATIONAL LIBRARY OF MEDICINE [T15LM007056] Funding Source: NIH RePORTER
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We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data (http://tilescope.gersteinlab.org). In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.
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