Journal
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
Volume 54, Issue 1, Pages 150-155Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TBME.2006.884647
Keywords
microwave liver ablation; temperature monitoring; water content
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We measured tissue temperature changes during ex vivo microwave ablation (MWA) procedures for bovine liver tissue. Tissue temperature increased rapidly at the beginning of the MW power application. It came to a plateau at 100 degrees C to 104 degrees C before it increased again. We split the changes of tissue temperature versus time into four phases. This suggests that tissue temperature changes may be directly related to tissue water related phenomena during MWA, including evaporation, diffusion, condensation and tissue water composition. An additional analysis indicated the lesion boundary at similar to 50 degrees C to 60 degrees C temperature. We also measured the water content of ablated tissue lesions and examined the relationship of tissue water content and tissue temperature by mapping temperature to remaining tissue water after ablation. The results demonstrate significant tissue water content changes and lead to a better understanding of tissue water movement.
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