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Transcranial Magnetic Stimulation in Child Neurology: Current and Future Directions

Journal

JOURNAL OF CHILD NEUROLOGY
Volume 23, Issue 1, Pages 79-96

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/0883073807307972

Keywords

transcranial magnetic stimulation; corticospinal pathway maturation; cortical reorganization; corticospinal abnormalities; cortical excitability; cortical plasticity

Funding

  1. NINDS [K23 NS046565, K24 RR018875]
  2. NATIONAL CENTER FOR RESEARCH RESOURCES [K24RR018875] Funding Source: NIH RePORTER
  3. NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [K23NS046565] Funding Source: NIH RePORTER

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Transcranial magnetic Stimulation (TMS) is a method for focal brain stimulation based on the principle of electromagnetic induction, where small intracranial electric currents are generated by a powerful, rapidly changing extracranial magnetic field. Over the past 2 decades TMS has shown promise in the diagnosis, monitoring, and treatment of neurological and psychiatric disease in adults, but has been used on a more limited basis in children. We reviewed the literature to identify potential diagnostic and therapeutic applications of TMS in child neurology and also its safety in pediatrics. Although TMS has not been associated with any serious side effects in children and appears to be well tolerated, general safety guidelines should be established. The potential for applications of TMS in child neurology and psychiatry is significant. Given its excellent safety profile and possible therapeutic effect, this technique should develop as an important tool in pediatric neurology over the next decade.

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