Journal
NATURE REVIEWS CANCER
Volume 8, Issue 4, Pages 309-316Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc2346
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Funding
- NATIONAL CANCER INSTITUTE [P01CA080124] Funding Source: NIH RePORTER
- NCI NIH HHS [P01 CA080124] Funding Source: Medline
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The importance of multidisciplinary translational clinical trials is obvious; however, making them work is complex and challenging. Here I present an argument for designing and implementing multidisciplinary mechanistic trials and present the lessons our team at the Massachusetts General Hospital Cancer Center has learned from two such trials in cancer patients with locally advanced rectal carcinomas and recurrent glioblastomas.
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