Formulation of microbial biocontrol agents - an industrial perspective

One of the key components to the commercial success of a biological control agent for plant pathogens is formulation. Formulation of biocontrol agents can be used to: stabilize the organisms during production, distribution and storage; aid in the handling and application of the product; protect the agent from harmful environmental factors; and enhance the activity of the organisms (Jones Burges, 1998). From a technical efficacy standpoint, an effective formulation requires thorough knowledge of the biocontrol organism, pathogen, environment, and interactions with other organisms. The development of a commercially-viable formulation also requires an understanding of common application practices and equipment, as well as the desires of customers for formulation handling. It is important to develop a clear vision of the product specifications before formulation research is started. Ingredients must be safe and acceptable to regulatory agencies in all areas where the product will be used. This review will focus on microbial biocontrol of plant pathogens, as seen from an industrial formulation-development standpoint.