Journal
GENE THERAPY
Volume 15, Issue 2, Pages 67-73Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.gt.3303066
Keywords
stem cells; adult stem cells; embryonic stem cells; cancer stem cells; regenerative medicine; stem cell physiology
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Funding
- NHLBI NIH HHS [HL70561, R01 HL070561-06, R01 HL070561] Funding Source: Medline
- NIAID NIH HHS [R01 AI080424] Funding Source: Medline
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL070561] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI080424] Funding Source: NIH RePORTER
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Stem cell research is at the heart of regenerative medicine, which holds great promise for the treatment of many devastating disorders. However, in addition to hurdles posed by well-publicized ethical issues, this emerging field presents many biological challenges. What is a stem cell? How are embryonic stem cells different from adult stem cells? What are the physiological bases for therapeutically acceptable stem cells? In this editorial review, I will briefly discuss these superficially simple but actually rather complex issues that surround this fascinating cell type. The goal of this special issue on stem cells in Gene Therapy is to review some fundamental and critical aspects of current stem cell research that have translational potential.
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