Journal
JOURNAL OF DERMATOLOGY
Volume 42, Issue 3, Pages 288-295Publisher
WILEY
DOI: 10.1111/1346-8138.12777
Keywords
chronic wound; cutaneous polyarteritis nodosa; diabetic foot ulcer; peripheral arterial disease; platelet-rich plasma; wound healing
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Funding
- National Center for Global Health and Medicine [24-205]
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Treatment for patients with chronic wounds is entering a new era, and autologous platelet-rich plasma (PRP) is among the most promising treatments. PRP contains a concentration of platelets obtained by centrifuging the patient's blood. Because it contains fibrin and high concentrations of growth factors, PRP is known to promote wound healing. In this study, we present five patients with chronic foot ulcers successfully treated with PRP in our institution. The patients had various underlying diseases: diabetes (n=2), peripheral arterial disease (n=1), both diabetes and peripheral arterial disease (n=1), and cutaneous polyarteritis nodosa (n=1). Also, we provide a description of PRP's mechanisms, advantages, and limitations.
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