Journal
CURRENT DIRECTIONS IN PSYCHOLOGICAL SCIENCE
Volume 17, Issue 3, Pages 198-202Publisher
SAGE PUBLICATIONS INC
DOI: 10.1111/j.1467-8721.2008.00574.x
Keywords
dementia; executive function; attention; inhibitory control; memory systems
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Evidence from longitudinal, experimental, and neuroimaging studies converge to indicate that psychological functions other than episodic memory are affected very early in the course of Alzheimer's disease and, indeed, may predate or influence the apparent memory deficits. Changes in personality and difficulty in executive function, especially in terms of attentional and inhibitory control, are especially prominent. Deficits in other types of memory (i.e., semantic memory, conditioning) can also be detected in the early stages of the disease. It is time to update existing diagnostic criteria for this form of dementia in terms of current knowledge of multiple and interacting brain systems.
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