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Control of cultivation processes for recombinant protein production: a review

Journal

BIOPROCESS AND BIOSYSTEMS ENGINEERING
Volume 31, Issue 1, Pages 21-39

Publisher

SPRINGER
DOI: 10.1007/s00449-007-0163-7

Keywords

fermentation processes; process modeling; control; supervision; fault detection; soft-sensing; neural networks

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The current state-of-the-art in control of cultivation processes for recombinant protein production is examined including the quantitative knowledge that can be activated for this purpose and the measurement techniques that can be employed for control at industrial manufacturing sites.

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