Journal
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE
Volume 89, Issue 4, Pages 465-470Publisher
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/V10-175
Keywords
metallacarborane; oligonucleotide; modified oligonucleotide; H-phosphonate chemistry
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Funding
- Polish Ministry of Science and Higher Education [K152/H03/2007/09]
- Institute for Medical Biology PAS
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Dans ce travail, on rapporte la synthese efficace d'oligonucleotides portant des metallacarboranes contenant du fer (3,3'-fer-1,2,1'2'-dicarbollide) sur un support solide en faisant appel a la methode du H-phosphonate. Cette methodologie versatile peut etre appliquee a la synthese d'oligomeres de l'ADN portant diverses unites metallacarboranes.
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