Journal
CANADIAN JOURNAL OF CHEMISTRY
Volume 87, Issue 12, Pages 1733-1737Publisher
CANADIAN SCIENCE PUBLISHING
DOI: 10.1139/V09-146
Keywords
sugar orthoesters; anhydrous sodium bicarbonate; protected glycosyl bromide
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Funding
- Chinese Academy of Sciences
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A facile and eco-friendly method for the preparation of sugar orthoesters by using anhydrous sodium bicarbonate is described. Various sugar orthoesers, including sugar-sugar orthoesters, were synthesized in good-to-excel lent yields by the reaction of a protected glycosyl bromide with an alcohol or sugar.
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