4.1 Article

A novel and efficient synthesis of bis(benzofuranyl)methanes and 2-benzofuran-1-nitroalkanes catalyzed by Bi(OTf)3

Journal

CANADIAN JOURNAL OF CHEMISTRY
Volume 86, Issue 9, Pages 875-880

Publisher

CANADIAN SCIENCE PUBLISHING
DOI: 10.1139/V08-091

Keywords

benzofuran; aldehyde; bis(benzofuranyl)methanes; Bi(OTf)(3); 2-benzofuran-1-nitroalkane

Funding

  1. National Natural Science Foundation of China [20676123]

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Bismuth (III) triflate-catalyzed Friedel-Crafts reactions between benzofuran and aldehydes in different solvents were investigated. Bis(benzofuranyl)methanes were obtained with good yields when acetonitrile was used as solvent vent, while in the case of nitromethane the multi-component reaction products, 2-benzofuran-1-nitroalkanes, were formed under similar conditions. A plausible mechanism is given.

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