4.3 Review

Evidence-based comprehensive treatments for early autism

Journal

Publisher

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/15374410701817808

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Funding

  1. NICHD NIH HHS [U19 HD035468, U19 HD035468-07, U19 HD35468-07] Funding Source: Medline
  2. NIDCD NIH HHS [R21 DC005574-03, R21 DC05574-03, R21 DC005574] Funding Source: Medline
  3. NIMH NIH HHS [R13 MH070772, R01 MH0683981, T32 MH073124, R01 MH068232, R21 MH0673631, R13 MH070772-01, R13 MH70772-01, R01 MH068232-01] Funding Source: Medline
  4. EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT [U19HD035468] Funding Source: NIH RePORTER
  5. NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH068232, T32MH073124, R13MH070772] Funding Source: NIH RePORTER
  6. NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS [R21DC005574] Funding Source: NIH RePORTER

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Early intervention for children with autism is currently a politically and scientifically complex topic. Randomized controlled trials have demonstrated positive effects in both short-term and longer term studies. The evidence suggests that early intervention programs are indeed beneficial for children with autism, often improving developmental functioning and decreasing maladaptive behaviors and symptom severity at the level of group analysis. Whether such changes lead to significant improvements in terms of greater independence and vocational and social functioning in adulthood is also unknown. Given the few randomized controlled treatment trials that have been carried out, the few models that have been tested, and the large differences in interventions that are being published, it is clear that the field is still very early in the process of determining (a) what kinds of interventions are most efficacious in early autism, (b) what variables moderate and mediate treatment gains and improved outcomes following intervention, and (c) the degree of both short-term and long-term improvements that can reasonably be expected. To examine these current research needs, the empirical studies of comprehensive treatments for young children with autism published since 1998 were reviewed. Lovaas's treatment meet Chambless and colleague's (Chambless et al., 1998; Chambless et al., 1996) criteria for well-established and no treatment meets the probably efficacious criteria, though three treatments meet criteria for possibly efficacious (Chambless & Hollon, 1998). Most studies were either Type 2 or 3 in terms of their methodological rigor based on Nathan and Gorman's (2002) criteria. Implications of these findings are also discussed in relation to practice guidelines as well as critical areas of research that have yet to be answered.

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