Journal
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
Volume 86, Issue 3, Pages 563-570Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/cjce.20073
Keywords
fluidization; radioactive particle tracking; particle segregation; conical fluidized bed
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Radioactive particle tracking (RPT) has been used to study the motion of the particulate phase in a bench-scale conical fluidized bed containing dried pharmaceutical granule. RPT revealed that there is a distinct circulation pattern of the granule with particles moving upwards at high velocities near the centre of the bed and falling slowly near the walls. There was also a localized region near the centre of the bed where particles moved downward rapidly. The particle size distribution (PSD) of the granule had an appreciable impact on particle motion with a wide PSD leading to larger fluctuations in particle velocity as well as poorer granule mixing.
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