Journal
CANADIAN JOURNAL OF CARDIOLOGY
Volume 26, Issue 9, Pages 489-496Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0828-282X(10)70455-4
Keywords
Cardiovascular disease; Fibre; Fish; Heart disease; Lignans; Nutrition; Polyunsaturated fatty acids
Categories
Funding
- Canadian Institutes of Health Research
- St Boniface Hospital and Research Foundation
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Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega (omega)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of omega-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based omega-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown.
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