4.4 Article

Hip Fracture Incidence from 1981 to 2009 in the Czech Republic as a Basis of the Country-Specific FRAX Model

Journal

CALCIFIED TISSUE INTERNATIONAL
Volume 90, Issue 5, Pages 365-372

Publisher

SPRINGER
DOI: 10.1007/s00223-012-9582-9

Keywords

Hip fracture; Osteoporotic fracture; FRAX; 10-year fracture probability

Funding

  1. Amgen, Czech Republic
  2. [MZd CR 0002372801]
  3. [MZd CR 0002384101]

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The aim of this study was to calculate rates of hospitalization for hip fracture and the incidence of hip fractures in the Czech Republic over a period of 29 years. A second aim was to use the most recent data to populate a FRAX(A (R)) model for the assessment of fracture probability in individual patients. Data on hospitalizations for hip fracture (1981-2009) and number of women and men with hip fractures (2000-2009) were obtained, and incidences were computed for the entire population a parts per thousand yen50 years of age. Incidence of hospitalization for hip fracture in the Czech population aged a parts per thousand yen50 years increased progressively by calendar year. Age-standardized incidence of hip fractures increased to 2004 but leveled off thereafter and decreased after 2005. Data for hip fracture risk in 2008 and 2009 and the death hazard were used to populate a Czech-specific FRAX model for the computation of 10-year fracture probability. The customized FRAX model, using the verified epidemiological data, will be used to identify patients at increased fracture risk.

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