4.8 Article

The Pfam protein families database

Journal

NUCLEIC ACIDS RESEARCH
Volume 36, Issue -, Pages D281-D288

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkm960

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Funding

  1. BBSRC [BB/F010435/1] Funding Source: UKRI
  2. MRC [G0100305] Funding Source: UKRI
  3. Biotechnology and Biological Sciences Research Council [BB/F010435/1] Funding Source: researchfish
  4. Medical Research Council [G0100305] Funding Source: researchfish

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Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam ( 22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI GenPept and on sequences from selected metage-nomics projects. Pfam is available on the web from the consortium members using a new, consistent and improved website design in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/), as well as from mirror sites in France (http://pfam.jouy.inra.fr/) and South Korea (http://pfam.ccbb.re.kr/).

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