Journal
HISTOPATHOLOGY
Volume 52, Issue 1, Pages 3-10Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-2559.2007.02888.x
Keywords
apocrine cysts; apocrine ductal carcinoma in situ; breast; cDNA expression arrays; molecular studies
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Apocrine change occurs in a spectrum of benign lesions in the female breast and is also demonstrated in a subgroup of in situ and invasive carcinomas. Recent research has focused on the molecular phenotype of both benign and malignant apocrine lesions. This review will briefly summarize the morphological characteristics and risk associations of the spectrum of apocrine proliferations, but will focus on the updated molecular studies of both in situ and invasive apocrine carcinomas.
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