A clinical evaluation of Biobrane ® and Suprathel® in acute burns and reconstructive surgery

Background: In the treatment of superficial partial-thickness burns, various skin substitutes and temporary dressings offer potential advantages over traditional treatments. Nonetheless, the search for an ideal temporary skin substitute or biosynthetic wound dressing is still a continuous quest. This research aimed to provide objective data on the long-term outcome of Biobrane (R) and Supratheri (R). Methods: Eight months after the initial burn treatment of Biobrane (R) and Suprathel (R), skin elasticity was measured objectively using a Cutometer (R) and the scarring process was quantified using the Vancouver Scar Scale (VSS). Results: The median healing time for patients treated with Biobrane (R) was up to 1.8 days shorter then the Suprathel (R) group. Regarding the Vancouver Scar Scale (VSS), neither the single parameter, nor the total score were significantly different in both groups. In comparison, the Biobrane (R) group demonstrated superior Cutometer (R) parameters in regards to maximal extension, elasticity, retraction and pliability. Despite higher levels of Biobrane (R) group, the differences in the viscoelastic analysis of both substitutes did not vary significantly. Conclusion: Using both substitutes, we observed satisfying results in superficial partial-thickness burn treatment, without any significant differences. Since the treatment of burned patients is associated with high socioeconomic load, the cost factor should be one of the most important criteria in dermal substitute selection. (C) 2011 Elsevier Ltd and ISBI. All rights reserved.