4.6 Article

The weak-acid preservative sorbic acid is decarboxylated and detoxified by a phenylacrylic acid decarboxylase, PadA1, in the spoilage mold Aspergillus niger

Journal

APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 74, Issue 2, Pages 550-552

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02105-07

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Funding

  1. Biotechnology and Biological Sciences Research Council [BB/D005388/1] Funding Source: Medline

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Resistance to sorbic and cinnamic acids is mediated by a phenylacrylic acid decarboxylase (PadA1) in Aspergillus niger. A. niger Delta padA1 mutants are unable to decarboxylate sorbic and cinnamic acids, and the MIC of sorbic acid required to inhibit spore germination was reduced by similar to 50% in Delta padA1 mutants.

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