Journal
JOURNAL OF BACTERIOLOGY
Volume 190, Issue 2, Pages 743-746Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.01135-07
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Funding
- Medical Research Council [MC_U105185859] Funding Source: Medline
- MRC [MC_U105185859] Funding Source: UKRI
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We present evidence that the agr cell-to-cell communication system is present across firmicutes, including the human pathogen Clostridium perfringens. Although we find that the agr system is evolutionarily conserved and that the general functions which it regulates are similar in different species, the individual regulated genes are not the same. This suggests that the regulatory network controlled by agr is dynamic and evolves rapidly.
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