4.7 Review

Elemental mass spectrometry for quantitative proteomics

Journal

ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 390, Issue 1, Pages 3-16

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00216-007-1615-2

Keywords

bioanalytical methods; genomics/proteomics; mass spectrometry/inductively coupled plasma mass spectrometry; speciation

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In the last decade mass-spectrometry-based proteomics has become an indispensable analytical tool for molecular biology, cellular biology and, lately, for the emerging systems biology. This review summarises the evolution and great potential of analytical methods based on elemental mass-spectrometric detection for quantitative proteomic analysis.

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