Journal
JOURNAL OF NUCLEAR MEDICINE
Volume 49, Issue 1, Pages 1-4Publisher
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.107.045799
Keywords
bioluminescence imaging; fluorescence imaging; optical imaging probes
Funding
- NATIONAL CANCER INSTITUTE [R24CA083099] Funding Source: NIH RePORTER
- NCI NIH HHS [R24 CA083099, R24CA083099] Funding Source: Medline
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Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy. Combining innovative molecular biology and chemistry, researchers have developed optical methods for imaging a variety of cellular and molecular processes in vivo, including protein interactions, protein degradation, and protease activity. Whereas optical imaging has been used primarily for research in small-animal models, there are several areas in which optical molecular imaging will translate to clinical medicine. In this review, we summarize recent advances in optical techniques for molecular imaging and the potential impact for clinical medicine.
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