A novel anthranilic acid based multi-component strategy for expeditious synthesis of 4(3H)-quinazolinone N-nucleosides

A one-pot montmorillonite K-10 clay-supported, three-component reaction of an substituted / unsubstituted anthranilic acid, ribosylamine and a substituted / unsubstituted benzoic acid expeditiously and rapidly yields a 2-aryl-3-(beta-D-ribofuranosyl)-3H-quinazolin-4-one as a novel N-nucleoside in excellent yield using microwave irradiation under solvent-free conditions.