Journal
NATURE GENETICS
Volume 40, Issue 1, Pages 23-25Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ng.2007.48
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Funding
- Wellcome Trust [071024] Funding Source: Medline
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Psoriasis is a common inflammatory skin disease with a strong genetic component. We analyzed the genomic copy number polymorphism of the beta-defensin region on human chromosome 8 in 179 Dutch individuals with psoriasis and 272 controls and in 319 German individuals with psoriasis and 305 controls. Comparisons in both cohorts showed a significant association between higher genomic copy number for beta-defensin genes and risk of psoriasis.
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