Journal
CLINICAL RHEUMATOLOGY
Volume 27, Issue 1, Pages 111-113Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s10067-007-0687-x
Keywords
antiphospholipid syndrome; catastrophic antiphospholipid syndrome; cyclophosphamide; HELLP syndrome; high-dose intravenous immunoglobulin therapy; plasmapheresis
Categories
Ask authors/readers for more resources
Authors present the first Hungarian case of a young pregnant woman with the association of antiphospholipid syndrome (APS) and hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. After the onset of severe preeclampsia, the pregnancy was terminated but the patient's condition continued to worsen. New symptoms of APS, including deep vein thrombosis and ischemic nervus opticus lesion, developed in the patient followed by the onset of acute respiratory distress syndrome, which required respiratory therapy. Intensive treatment with plasmapheresis, high-dose intravenous immunoglobulin, high-dose corticosteroids, cyclophosphamide, and anticoagulants eventually led to full recovery. There have been only few scattered reports in the literature on the association of HELLP syndrome and APS, which was successfully managed with the combination of various immunosuppressive and immunomodulatory treatment modalities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available