Journal
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume 33, Issue 12, Pages 3957-3962Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.5012/bkcs.2012.33.12.3957
Keywords
Amino acid; Arginine; Lysine; Magnetic nanoparticles; Synthesis
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Funding
- Tabriz University of Medical Sciences
- Shiraz University of Medical Sciences
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Iron-oxide nanoparticles (IONs) with biocompatible coatings are the only nanostructural materials which have been approved by the FDA for clinical use. Common biocompatible coatings such as hydrocarbons, polymers, and silica have profound influences on critical characteristics of IONs. Recently, amino acids were introduced as a novel biocompatible coating. In the present study, the effects of amino acids on IONs synthesis and characteristics have been evaluated. Magnetite nanoparticles with L-arginine and L-lysine coatings were synthesised by a coprecipitation reaction in aqueous solvent and their characteristics were compared with naked magnetite nanoparticles. The results showed that amino acids can be a perfect coating for IONs and would increase particle stability without any significant effects on the critical properties of nanoparticles such as particle size and magnetization saturation value.
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