Journal
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
Volume 31, Issue 10, Pages 2771-2775Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.5012/bkcs.2010.31.10.2771
Keywords
Biogenic; AuNPs; Cell viability assay; Nontoxic green product
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Funding
- Ministry of Education, Science and Technology, Republic of Korea [M1071118001-08M1118-00110]
- HYU [HY-2010-HYURS]
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We present a rapid biogenic method for the production of nanoscale gold particles using pear extract. The formation and stability of pear-derived gold nanoparticles (Pear-AuNPs) were monitored by ultraviolet-visible spectroscopy. Their morphology, elemental composition and crystalline phase were determined by transmission electron microscopy, energy-dispersive X-ray spectroscopy and selected area electron diffraction. The average core size of crystalline Pear-AuNPs was in the range of 10 +/- 5 nm and the observed morphology was spherical. The X-ray photoelectron spectrum showed a strong peak for the pure 'Au' phase. The circular dichroism spectrum indicated the natural capping ability of the pear extract, which generated peptide-gold nanoparticles. These nanoparticles were stable in aqueous solution for two months. A cell viability assay of Pear-AuNPs showed biocompatibility with human embryonic kidney 293 cells. Accordingly, this eco-friendly process for the bio-mimetic production of Pear-AuNPs is nontoxic in nature; consequently, it will find potential application in nano-biotechnology.
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