4.2 Article

Mechanism of Targeted Migration of Mesenchymal Stem Cells

Journal

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 153, Issue 4, Pages 577-580

Publisher

SPRINGER
DOI: 10.1007/s10517-012-1770-0

Keywords

apoptosis; cell therapy

Funding

  1. Russian Foundation for Basic Research [11-04-00993-a]

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Experiments performed on mice C57Bl/6 with the use of GFP technology showed that activation of apoptosis is a potent physiological stimulus for targeted migration of mesenchymal stem cell from the blood to tissues. The effect of apoptosis-induced targeted migration of stem cells can be used in cell therapy of damaged organs and tissues in various pathological states.

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