Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 150, Issue 5, Pages 587-589Publisher
SPRINGER
DOI: 10.1007/s10517-011-1197-z
Keywords
hypertension; spontaneously hypertensive rats; calcium paradox; calcium-dependent calpain protease
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Females of spontaneously hypertensive (SHR strain) and normotensive rats (WKY strain and Wistar) received drinking water with normal (80 mg/liter) or reduced concentration of Ca(2+) (8 mg/liter). Activity of calcium-dependent calpain protease in neurons did not differ in 18-day-old rat pups born and suckled by these animals. Our results are consistent with published data on normal metabolism of SHR rats up to the age of 30 days.
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