Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 150, Issue 1, Pages 117-121Publisher
SPRINGER
DOI: 10.1007/s10517-010-1084-z
Keywords
vitreous body; lens; retina; vasculogenesis and angiogenesis; transforming growth factor-beta(2) (TGF-beta(2))
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Funding
- Russian Foundation for Basic Research [08-04-00462, 09-04-01054a]
- Presidium of the Russian Academy of Medical Sciences
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Expression of transforming growth factor-beta(2) was detected by PCR in the vitreous body, lens, retina, and ciliary-iris complex of human eye at early stages of fetal development. Immunochemical assay of the corresponding protein in eye tissues revealed a correlation between the localization of transforming growth factor-beta(2) and the development of intraocular hyaloid vascular network, its regression, formation of the vitreous body, and development of definite retinal vessels.
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