Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 147, Issue 1, Pages 132-146Publisher
SPRINGER
DOI: 10.1007/s10517-009-0432-3
Keywords
brain trauma; mesenchymal stem cells; neural stem cells; xenotransplantation; neurogenesis
Categories
Funding
- Diod Company
Ask authors/readers for more resources
We studied the effect of transplantation of human stem cells from various tissues on reparative processes in the brain of rats with closed craniocerebral injury. Combined treatment with standard drugs and systemic administration of xenogeneic stem cells had a neuroprotective effect. The morphology of neurons rapidly returned to normal after administration of fetal neural stem cells. Fetal mesenchymal stem cells produced a prolonged effect on proliferative activity of progenitor cells in the subventricular zone of neurogenesis. Adult mesenchymal stem cells had a strong effect on recovery of the vascular bed in ischemic regions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available