Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 147, Issue 1, Pages 66-69Publisher
SPRINGER
DOI: 10.1007/s10517-009-0445-y
Keywords
fucoidans; hemostasis; immunity; cytokines; lipopolysaccharides
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Fucoidan extracted from brown algae (Fucus evanescens) was used for correction of immunity and hemostasis disorders in experimental endotoxemia induced by injection of LPS. Fucoidan reduced the elevated levels of proinflammatory cytokines (TNF-alpha, IL-1, IL-6) and partially arrested hypercoagulation phenomena, thus improving animal resistance to LPS.
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