Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 148, Issue 1, Pages 54-56Publisher
SPRINGER
DOI: 10.1007/s10517-009-0638-4
Keywords
antidepressant activity; Azafen; Paroxetine; Tianeptin
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Antidepressant activity of Russian product Azafen (pipofezine) and foreign products Paroxetine and Tianepine was compared using behavioral despair test (Porsolt test) and forced swimming test in a container with wheels (Nomura). Azafen signifi cantly shortened the duration of depressive state in both tests. The results suggest that Azafen exhibits pronounced antidepressant activity, superior to that of the reference drugs.
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