Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 145, Issue 3, Pages 352-354Publisher
SPRINGER
DOI: 10.1007/s10517-008-0089-3
Keywords
Trypanosoma cruzi; Ehrlich's adenocarcinoma; antitumor activity; immunocompetent cells
Categories
Ask authors/readers for more resources
The experiments with passive transfer of splenocytes obtained from animals immunized with Trypanosoma cruzi lysate revealed the role of cell-mediated component of the immunity in the antitumor effect of T. cruzi. The common features of T. cruzi antigens and tumor-specific antigens of Ehrlich's adenocarcinoma were demonstrated. These antigens were shown to have common epitopes with mammalian mucins. The oncoprotective effect was achieved by immunization with type II and III mucins and was reproduced after passive transfer of splenocytes from immunized animals.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available