Journal
CURRENT DIABETES REVIEWS
Volume 5, Issue 4, Pages 216-220Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157339909789804396
Keywords
Fibroblast growth factor 21; Glucose; Energy balance; Insulin; Metabolic syndrome; Type 2 diabetes mellitus
Categories
Ask authors/readers for more resources
FGF21 is a novel member of the FGFs family, is mainly expressed in liver and it functions as a potent activator of glucose uptake on adipocytes. When over expressed in transgenic mice, it protects animals from diet-induced obesity and its administration to diabetic rodents and monkeys lowers blood glucose and triglyceride levels. Recently, increased levels of FGF21 have been identified as an independent risk factor related with metabolic syndrome. A review of the relevant roles of FGF21 in metabolism is presented here.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available