4.6 Editorial Material

Metabotropic glutamate receptor agonists for schizophrenia

Journal

BRITISH JOURNAL OF PSYCHIATRY
Volume 192, Issue 2, Pages 86-87

Publisher

ROYAL COLLEGE OF PSYCHIATRISTS
DOI: 10.1192/bjp.bp.107.045088

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Funding

  1. Medical Research Council [G0801747] Funding Source: researchfish
  2. MRC [G0801747] Funding Source: UKRI
  3. Medical Research Council [G0801747] Funding Source: Medline

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A drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.

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