Journal
BRITISH JOURNAL OF PSYCHIATRY
Volume 193, Issue 5, Pages 424-425Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.bp.107.040501
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Funding
- NIMH [R01MH067073]
- Dana Foundation
- NIH/NCRR/GCRC [RR00125]
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The time course of brain activation prior to onset of auditory/ verbal hallucinations was characterised using functional magnetic resonance imaging in six dextral patients with schizophrenia. Composite maps of pre-hallucination periods revealed activation in the left anterior insula and in the right middle temporal gyrus, partially replicating two previous case reports, as well as deactivation in the anterior cingulate and parahippocampal gyri. These findings may reflect brain events that trigger or increase vulnerability to auditory/verbal hallucinations. Declaration of interest None. Funding detailed in Acknowledgements.
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