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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor
YQ Chen et al.
SCIENCE (2000)
Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides
J Bylund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes ΔΨm loss, caspase-9 activity, and apoptosis in Jurkat cells
S Gamen et al.
EXPERIMENTAL CELL RESEARCH (2000)
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
TM Loftus et al.
SCIENCE (2000)
Expression cloning of an oxysterol 7α-hydroxylase selective for 24-hydroxycholesterol
J Li-Hawkins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cloning and characterization of the human and mouse PDE7B, a novel cAMP-specific cyclic nucleotide phosphodiesterase
C Gardner et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Identification of human PDE7B, a cAMP-specific phosphodiesterase
T Sasaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton
LQ Dong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
N-[[(5-methyl-3-phenylisoxazol-4-yl)-phenyl] sulfonyl]propanamide, sodium salt, parecoxib sodium:: A potent and selective inhibitor of COX-2 for parenteral administration
JJ Talley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury
MM Mocanu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models
T Ochi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
Nitric oxide selectively inhibits adenylyl cyclase isoforms 5 and 6
J Hill et al.
CELLULAR SIGNALLING (2000)
Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities
JD Corbin et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity
T Sudo et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
TD Butters et al.
TETRAHEDRON-ASYMMETRY (2000)
Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase
JD Bergstrom et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Pharmacological characterization of a novel sulfonylureid-pyrazole derivative, SM-19712, a potent nonpeptidic inhibitor of endothelin converting enzyme
K Umekawa et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2000)
A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients
G Sjoholt et al.
MOLECULAR PSYCHIATRY (2000)